PathMaker Neurosystems Inc.

medical devices

About

PathMaker Neurosystems Inc. is a clinical-stage company focused on developing non-invasive medical devices for treating amyotrophic lateral sclerosis (ALS) and other serious neurological disorders. The company utilizes a novel approach called multi-site direct current stimulation (Multi-Site DCS) technology, which modulates neuronal activity to restore damaged neural pathways. Their goal is to transform ALS from a fatal disease into a livable condition through innovative neuromodulation therapies. The company’s devices aim to suppress motor neuron hyperexcitability and activate protein degradation pathways to reduce toxic protein aggregates, such as TDP-43 and SOD1, in motor neurons. PathMaker Neurosystems has conducted extensive preclinical studies and human clinical trials, supported by funding from the NIH and other organizations. They primarily target patients with ALS and other neurological disorders, working with healthcare providers and seeking partnerships with institutional investors committed to advancing treatments in this field.

Technologies

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Keywords

neuroscience noninvasive stimulation neuromodulation bioelectronic medicine als medical equipment manufacturing services clinical-stage clinical trials neuromodulation devices molecular mechanisms bioelectronic therapy motor neuron disease disrupted neural pathways protein aggregation reduction medical equipment and supplies manufacturing neural pathway restoration medical devices als treatment healthcare neural circuit modulation neuroscience research non-invasive neuromodulation biotechnology multi-site dcs technology neurological disorders proprietary technology healthcare technology neurological rehabilitation electrical stimulation

Location

1 International Pl, Boston, Massachusetts, United States, 02110

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