Relief Cardiovascular

Relief Cardiovascular is a medical device company based in Orange County, California, founded in 2022. The company focuses on developing, manufacturing, and commercializing advanced heart valves, active implants, and catheter-based technologies aimed at addressing congestive heart failure (CHF). Their mission is to alleviate the challenges of CHF through innovative transcatheter smart implant systems that enhance volume management for heart failure patients. The flagship product, the Relief System, is the first transcatheter preload modulating implant designed to autonomously monitor and adjust renal vein pressures. This system improves fluid management in heart failure by dynamically regulating venous return, particularly benefiting patients with diuretic-resistant heart failure. The Relief System features integrated sensors for capturing renal vein pressures and multiparametric data, allowing for personalized therapy adjustments. The company is advancing this technology into clinical investigation outside the U.S., with a first-in-human feasibility study planned for late 2025, supported by significant financing from various investors.

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